Bifidobacterium longum (B. longum) which has an interesting "Y" shape can protect the cells that line the mucosa from toxins and allow some of the immune cells to mature and function properly.
Due to antagonistic effect of microorganisms, its antagonistic strains may also evolve into probiotics. CD BioSciences provides an advanced technology platform for B. longum-based probiotics screening service. Our MicroScanTM technology platform is development to meet customer's personalized customization needs.
Overview of B. longum
- B. longum which was isolated from the infant and adult intestines is a type of probiotic. It belongs to the genera Actinomyces and Bifidobacterium. The species of B. longum include three subspecies, longum, infantis, and suis.
- B. longum is often discovered in the human gastrointestinal tract. B. longum communicates with other microorganisms in the gut, allowing them to produce short-chain fatty acids which helps lower the hygienic group PH, making the environment less suitable for pathogenic bacteria. It is highly stable in various finished products, including fermented milk.
Applications of B. longum
- Improve Gut Health
B. longum improves the intestinal environment and reduces gastrointestinal problems. It helps maintain normal immune regulation in humans.
- Colon Cancer Prevention
Oral administration of B. longum significantly inhibited the incidence of colon tumors and tumor multiplication rates, and reduced tumor volume. The effects on colon cancer provide a new idea for the treatment of cancer.
- Relief of Atopic Dermatitis
B. longum stimulates increased tryptophan metabolism in people suffering from atopic dermatitis, thereby relieving the associated symptoms.
- Anti-anxiety
Preliminary results from the study show that the combination of B. longum and Lactobacillus herbeticus reduces stress-related gastrointestinal disorders. The combination showed anxiolytic effects and a positive psychological effect in human volunteer species.
- Avoid Excessive Obesity
B. longum can help people maintain a normal body weight and avoid excessive obesity.
Applications of B. longum
Our Services
CD BioSciences provides probiotics screening service using B. longum as an indicator strain. Our MicroScanTM technology platform can discovery bacteria strains that promote the growth of the indicator strain, which together can be further developed as probiotics. This platform provides a new approach for screening and detecting microbial interactions and it can be applied to any microbial flora.
- Single Bacteria Strain Discovery
Identifying single bacterial stains that can be mixed with B. longum - Combination of Bacteria Strains Discovery
Identifying a mixture of bacteria strains that can be mixed with B. longum
Features of Our Services
- With rich resource bases on probiotic strains, CD BioSciences supports scientific research strongly.
- In the help of a professional team, can get your results within your expectations.
- To free you from hassles, we offer a one-stop service.
CD BioSciences is committed to providing professional and efficient service to our customers around the world. As a pioneer in biotechnology, CD BioSciences has grown into one of the largest independent biotechnology companies in the world. If you are interested in our service, please contact us.
References
- Landete, J. M. et al. (2014). "Anaerobic green fluorescent protein as a marker of Bifidobacterium strains." Int J Food Microbiol. 175: 6-13.
- Chyn, B. W. et al. (2019). "Beneficial effects of Bifidobacterium longum subsp. longum BB536 on human health: Modulation of gut microbiome as the principal action." Journal of Functional Foods. 54.
- Fang, Z. et al. (2022). "Bifidobacterium longum mediated tryptophan metabolism to improve atopic dermatitis via the gut-skin axis." Gut Microbes. 14 (1): 2044723.