Staphylococcus aureus (S. aureus) is an important pathogenic bacterium that causes a wide range of serious infections. During antibiotic treatment, the evolution of S. aureus has produced multi-drug resistant strains. Currently, there is still no specific drug for S. aureus. New antibiotics still need to be developed.
Traditional inhibition circle screening to discover antibiotics is time-consuming and laborious, so a novel method is needed. CD BioSciences provides an advanced technology platform for S. aureus-based pathogenic bacteria screening service. Our MicroScanTM technology platform is development to meet customer's personalized customization needs.
Overview of S. aureus
Basics about S. aureus
- S. aureus is a Gram-positive round-shaped bacterium. It is a symbiont and opportunistic pathogen of the human microbiome.
- In 1884, the German scientist Friedrich Julius Rosenbach identified S. aureus.
Toxicity Factors of S. aureus
- S. aureus typically promotes infections by producing virulence factors, such as potent protein toxins, and by expressing cell surface proteins that bind and inactivate antibodies.
- The Infections can be treated with penicillin, but the emergence of methicillin-resistant S. aureus strains have made it difficult for penicillin to kill this bacterium.
Types of Diseases Caused by S. aureus
- Skin Diseases
Overgrowing and secreting toxins, S. aureus causes dysbiosis of the human skin microbiota and leads to conditions such as atopic dermatitis and psoriasis - Respiratory Diseases
S. aureus enters the respiratory cells and stimulates the production and release of cytokines such as airway epithelium and inflammatory vesicles, induced by its own proteins as well as virulence factors. These factors lead to a series of strong immune responses and the occurrence of asthma, chronic rhino sinusitis, and pneumonia diseases. - Food Poisoning
After contamination of food, S. aureus enters the cells of the gastrointestinal tract along with the food, which can easily lead to intestinal inflammation. - Osteomyelitis
S. aureus is the main causative agent of osteomyelitis, accounting for 80% of all osteomyelitis cases. - Autoimmune Diseases
The products of S. aureus are a common departure factor of granulomatosis with polyangiitis.
Types of diseases caused by S. aureus. (Chen, H. et al. ,2022)
Our Service
CD BioSciences provides probiotics screening service using S. aureus as an indicator strain. Our MicroScanTM technology platform can discovery bacteria strains that Inhibit the growth of the indicator strain, which perhaps generate new antibacterial drugs as antibiotics. This platform provides a new approach for screening and detecting microbial interactions and it can be applied to any microbial flora.
- Single Bacteria Strain Discovery
Identifying single bacterial stains that can be mixed with S. aureus - Combination of Bacteria Strains Discovery
Identifying a mixture of bacteria strains that can be mixed with S. aureus
Features of Our Services
- Advanced Technology
CD BioSciences has a rich resource of pathogenic bacteria strains and a professional laboratory that strongly supports scientific research.
- Fast Delivery
You are guaranteed to submit your results within your expected time.
- Comprehensive Service
Professional pre-sales, in-sales and after-sales service to answer your questions in detail.
CD BioSciences is committed to providing professional and efficient service to our customers around the world. As a pioneer in biotechnology, CD BioSciences has grown into one of the largest independent biotechnology companies in the world. If you would like more information, please contact us.
Reference
- Chen, H. et al. (2022). "Exploring the Role of S. aureus in Inflammatory Diseases." Toxins (Basel). 14 (7).