Streptococcus pneumoniae (S. pneumoniae) can cause a variety of diseases, and a few strains are infectious. Currently, due to the irrational use of antibiotics and mutation of strains，the resistance of S. pneumoniae to different antibiotics is increasing. New antibacterial substances are urgently needed for human beings.
For rapid identification of strains producing new antibacterial substances, CD BioSciences provides an advanced technology platform for S. pneumoniae-based pathogenic bacteria screening service. Our MicroScanTM technology platform is development to meet customer's personalized customization needs.
Overview of S. pneumoniae
Basics about S. pneumoniae
- The typical S. pneumoniae is a Gram-positive coccus, often arranged in pairs.
- S. pneumoniae was first isolated from patient sputum in 1881 in France and the United States by Louis Pasteur and G. M. Sternberg, respectively.
Toxicity Factors of S. pneumoniae
- The polysaccharide capsule is the most important pathogenic factor of S. pneumoniae. Diseases caused by S. pneumoniae can be treated with penicillin.
- S. pneumoniae repels phagocytosis by leukocytes under the action of the negative charge of their polysaccharide molecules, which help the bacteria escape from the host immune system for detection and bactericidal function.
Types of Diseases Caused by S. pneumoniae
- Community Acquired Pneumonia
Community-acquired pneumonia is caused out-of-hospital by a variety of microorganisms, including bacteria, viruses, chlamydia and mycoplasma. Of these, morbidity and mortality caused by S. pneumoniae is the most common.
- Bacteremia
The accumulation of S. pneumoniae leads to wind infections and various septic infections that enter the blood vessels and cause bacteremia.
- Otitis Media
Acute otitis media caused by S. pneumoniae is common to children, and the infection is mainly caused by invasion of the Eustachian tube or tympanic membrane.
- Meningitis
S. pneumoniae meningitis is a common purulent meningitis in adults. The pathogen multiplies rapidly and the exudation contains a large amount of fibrin, which tends to cause adhesion.
Types of diseases caused by S. pneumoniae. (Bogaert, D. et al., 2004)
Our Service
CD BioSciences provides probiotics screening service using S. pneumoniae as an indicator strain. Our MicroScanTM technology platform can discovery bacteria strains that Inhibit the growth of the indicator strain, which perhaps generate new antibacterial drugs as antibiotics. This platform provides a new approach for screening and detecting microbial interactions and it can be applied to any microbial flora.
- Single Bacteria Strain Discovery
Identifying single bacterial stains that can be mixed with S. pneumoniae - Combination of Bacteria Strains Discovery
Identifying a mixture of bacteria strains that can be mixed with S. pneumoniae
Features of Our Services
- Advanced Technology
CD BioSciences has a rich resource of pathogenic bacteria strains and a professional laboratory that strongly supports scientific research.
- Fast Delivery
You are guaranteed to submit your results within your expected time.
- Comprehensive Service
Professional pre-sales, in-sales and after-sales service to answer your questions in detail.
CD BioSciences is committed to providing professional and efficient service to our customers around the world. As a pioneer in biotechnology, CD BioSciences has grown into one of the largest independent biotechnology companies in the world. If you would like more information, please contact us.
References
- Feldman, C. and R. Anderson. (2020). "The Role of S. pneumoniae in Community-Acquired Pneumonia." Semin Respir Crit Care Med. 41 (4): 455-469.
- Bogaert, D. et al. (2004). "S. pneumoniae colonisation: the key to pneumococcal disease." Lancet Infect Dis. 4 (3): 144-54.